WELCOME TO SUNG LAB!
We use biochemical, genetic and cell biological tools to study DNA repair mechanisms. We are actively engaged in training the next generation of scientists and are always looking to recruit outstanding postdoctoral fellows to join our lab. Our research is generously supported by the National Institutes of Health (NIH), Cancer Prevention and Research Institute of Texas (CPRIT) and UT Health San Antonio.
We are excited to announce that Arijit has received a Postdoctoral Scholar Fellowship from the Office of Postdoctoral Affairs (formerly SALSI) at UT Health San Antonio. Arijit is working on the role of BRCA pathway in resolution of R-loops at DNA break …
We welcome our newest postdoc, Dr. Cody Rogers, who comes to us from Indiana University and will be working on the BRCA proteins and their partners. Cody’s work will be supported by the NIA T32 Biology of Aging Training Grant. Congratulations and Welco …
We are thrilled to announce that Ajinkya has received a CPRIT Postdoctoral Fellowship for his project titled “Mechanism of Shieldin-mediated regulation of DSB repair pathway choice” and will be appointed on the Research Training Award for 2 years. Cong …
Steinfeld JB, Beláň O, Kwon Y, Terakawa T, Al-Zain A, Smith MJ, Crickard JB, Qi Z, Zhao W, Rothstein R, Symington LS, Sung P, Boulton SJ, Greene EC. Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination. Genes Dev. 2019 Aug 1. doi: 10.1101/gad.328062.119
Bai Y, Wang W, Li S, Zhan J, Li H, Zhao M, Zhou XA, Li S, Li X, Huo Y, Shen Q, Zhou M, Zhang H, Luo J, Sung P, Zhu WG, Xu X, Wang J. C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex. Mol Cell. 2019 Jul 9. pii: S1097-2765(19)30479-4. doi: 10.1016/j.molcel.2019.06.023
Liang F, Miller AS, Longerich S, Tang C, Maranon D, Williamson EA, Hromas R, Wiese C, Kupfer GM, Sung P. DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response. Nat Commun. 2019 Jun 28;10(1):2849. doi: 10.1038/s41467-019-10408-5.
Zhao W, Wiese C, Kwon Y, Hromas R, Sung P. The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination. Annu Rev Biochem. 2019 Jun 20;88:221-245. doi: 10.1146/annurev-biochem-013118-111058